The Best Cities in Mexico and Central and South America in 2016

Dave Lauridsen

From Mexico, through Central America, and to the farthest reaches of South America, visitors to this part of the world can encounter dozens of dynamic cities.

Every year for our World’s Best Awards survey, T+L asks readers to weigh in on travel experiences around the globe — to share their opinions on the top hotels, resorts, cities, islands, cruise lines, spas, airlines, and more. Readers rated cities on their sights and landmarks, culture, food, friendliness, shopping, and overall value.

For the 11th year in a row, Cuzco and Buenos Aires appeared on the list, though the latter fell in rank, ousted by newcomers like Oaxaca and Mendoza.

Five of Mexico's cities made this year's list, a stat at least partially explained by a fresh crop of notable hotels and resorts.

But it’s not typical resort destinations that captivated our readers in 2016. It was quiet, colonial cities like Mérida and inland destinations like Oaxaca that impressed travelers seeking Mayan archaeological sites, embroidered textiles, and regional food.

Read on for the full list of unforgettable Mexican and Central and South American cities.

Start Slideshow

1 of 10

No. 10: Buenos Aires, Argentina

Getty Images

Score: 82.72

2 of 10

No. 9: Bogotá, Colombia

Bloomberg via Getty Images

Score: 82.789

3 of 10

No. 8: Guadalajara, Mexico

UIG via Getty Images

Score: 85.303

Book a trip to Guadalajara.

4 of 10

No. 7: Mendoza, Argentina

Itsmemarttin, CC BY-SA 3.0 via Wikimedia Commons

Score: 85.369

5 of 10

No. 6: Antigua Guatemala, Guatemala

Anadolu Agency / Getty Images

Score: 85.917

6 of 10

No. 5: Mérida, Mexico

Volunteer Abroad UBELONG via Flickr.com / CC BY-NC 2.0

Score: 86.286

7 of 10

No. 4: Mexico City, Mexico

Luis García

Score: 86.632

Book a trip to Mexico City.

8 of 10

No. 3: Oaxaca, Mexico

Lindsay Lauckner Gundlock

Score: 88.56

9 of 10

No. 2: Cuzco, Peru

Getty Images/Robert Harding World Imagery

Score: 88.958

10 of 10

No. 1: San Miguel de Allende, Mexico

Dave Lauridsen

Score: 91.191

The city has seen a significant transformation in the past few years, drawing in expats and tourists with its global food scene and beautiful Spanish-colonial architecture. A UNESCO World Heritage site, San Miguel de Allende possesses a certain mountain-town charm that not all cities have: its friendly local feel is matched only by its energy and festivals. As one T+L voter described, “the plaza is their living room. [It's] an art lover’s paradise.”

Replay gallery

World's Best

The 50 Best Places to Travel in 2020

Let's Go Together Podcast

The Best Cities in Mexico and Central and South America in 2016

1 of 10

No. 10: Buenos Aires, Argentina

1 of 10

2 of 10

No. 9: Bogotá, Colombia

2 of 10

3 of 10

No. 8: Guadalajara, Mexico

3 of 10

4 of 10

No. 7: Mendoza, Argentina

4 of 10

5 of 10

No. 6: Antigua Guatemala, Guatemala

5 of 10

6 of 10

No. 5: Mérida, Mexico

6 of 10

7 of 10

No. 4: Mexico City, Mexico

7 of 10

8 of 10

No. 3: Oaxaca, Mexico

8 of 10

9 of 10

No. 2: Cuzco, Peru

9 of 10

10 of 10

No. 1: San Miguel de Allende, Mexico

10 of 10

Up Next

Everything in This Slideshow

Your Profile

The Best Cities in Mexico and Central and South America in 2016

1 of 10

No. 10: Buenos Aires, Argentina

1 of 10

2 of 10

No. 9: Bogotá, Colombia

2 of 10

3 of 10

No. 8: Guadalajara, Mexico

3 of 10

4 of 10

No. 7: Mendoza, Argentina

4 of 10

5 of 10

No. 6: Antigua Guatemala, Guatemala

5 of 10

6 of 10

No. 5: Mérida, Mexico

6 of 10

7 of 10

No. 4: Mexico City, Mexico

7 of 10

8 of 10

No. 3: Oaxaca, Mexico

8 of 10

9 of 10

No. 2: Cuzco, Peru

9 of 10

10 of 10

No. 1: San Miguel de Allende, Mexico

10 of 10

Share the Gallery

Up Next

Share the Gallery