If you’re itching to get away this week–and really, who isn’t?—we have one for the record books: almost 50% off at twelve T+L-reviewed hotels from New Mexico to the Caribbean, even London during the Royal Wedding. Scroll down for some of the deals.

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Hyatt Regency Tamaya Resort & Spa- up to 48% off
Santa Ana Pueblo, New Mexico

This Pueblo-style resort halfway between Santa Fe and Albuquerque offers authentic Tamaya activities (tribal folk-dance shows, huruna-bread tastings, pottery-making lessons) in addition to golf, horseback riding, and post-adventure pampering (try the ancient-drumming mud mask). It's all part of the draw at this sprawling Native American-owned hotel near Bernalillo. Spend the night in one of the resort's roomy Mountain Vista units, which have slate-bathroom floors, southwestern-print down blankets, and grand balconies or patios overlooking the Sandias. (Sale ends in 1 day.)

St. James's Club Resort & Villas - up to 55% off
St John's, Antigua and Barbuda

Spread across 100 acres of a peninsula on the island's southeastern coast, this resort's rooms and villas are done in an airy, tropical style, with wicker furnishings, terracotta tile floors, and colorful prints and fabrics. One beach faces east and the other west, so both sunrise and sunset can be enjoyed from the sand. And with recent upgrades to its four restaurants, the addition of an adults-only pool, and the opening of 50 all-inclusive Royal Suites on the beach, St. James's seems to have vanquished any shortcomings inherited from its old incarnation as a Holiday Inn. (Sale ends in 5 days.)

The Landmark London - up to 42% off
London, United Kingdom

Opened in 1899, this Gothic Revival masterpiece was to be London's gateway to the Continent via a railway link to the impending Channel tunnel. Alas, financiers overshot tunnel construction by a century, rail travel declined, and the hotel fell into disrepair. Restored in the 1990s to former clock-towered, stained-glass, marble-columned glory, the Landmark is adjacent to the Marylebone Tube station and a hop-skip to Regent's Park and Baker Street. About half of the 300 traditionally decorated rooms overlook the Winter Garden restaurant's stunning eight-story central atrium with full-size palm trees. (Sale ends in 5 days.)

Image Courtesy of and Hyatt Regency Tamaya Resort & Spa