Passengers lucky enough to snag one of the 548 staterooms aboard Crystal Cruises' third ship will be sailing in style. Launched in July, the Crystal Serenity provides the standard luxury-liner accoutrements—a spa, a casino, Broadway-worthy entertainment—and then some. Crystals' Creative Learning Institute brings experts on board to guide classes that promote learning and personal enhancement. Nobu Matsuhisa created the menu and trained the chefs at his sushi bar (there are four additional restaurants). All guest quarters are outside berths, and 85 percent have their own verandas. Penthouse suites, the first type of room to sell out on Crystal's two other vessels, have increased in both size and number and come with that staple found on ships of yesteryear, the white-gloved butler. If you can dream it up, your wish will come true, be it a dinner for two on a secluded terrace, a guided hike up Mount Etna, or a private tour of Bordeaux's boutique vineyards. Crystal Serenity, 800/768-9955;; 12-day Mediterranean and Western European sailings from $3,995 per person, double.
—Heidi S. Mitchell