Set on an island in the heart of Moscow, the once-abandoned warehouses of the old Red October chocolate factory now house some of the city’s hippest galleries, restaurants, and rooftop bars.

For classic cucina italiana, check out Bontempi, a new locanda from Lombardy-born chef Valentino Bontempi. 12 Bersenevskaya Nab.; 7-495/223-1387; dinner for two $138.

With its spacious roof deck and innovative tapas (bocconcini and chile fritters), Bar Strelka—atop the Strelka design institute—draws a mix of local artists, intellectuals, and scenesters. 14 Bersenevskaya Nab.; 7-495/771-7437; drinks for two $25.

Take in realist artworks from the Soviet era at the new Lumière Brothers Center of Photography. 3 Bolotnaya Nab.; 7-495/223-1387.

Dine on thin-crust Neapolitan pies alongside digital sculptures by Russian design collective Eletroboutique at the hybrid restaurant, gallery, and nightspot Art Academiya. 6 Bersenevskaya Nab.; 7-495/771-7446; dinner for two $80.

At the cinema-themed bar Dome, drinks are served in a screening room that plays Russian art-house films and Hollywood classics. There’s also a separate cocktail lounge. 3/10 Bersenevskiy Per.; 7-499/788-6524; drinks for two $28.

The boutique Russian Street stocks fashion-forward pieces by dozens of up-and-coming local designers. 8 Bersenevskaya Nab.; 7-495/771-0614.