By Amy Brownlee
September 05, 2013

Over-the-Rhine (OTR)—known for its Italianate architecture—has gone from historic to hip.

Inventive Japanese gastropub and sushi bar Kaze amps up its ramen with littleneck clams and red miso broth; turkey sliders are piled high with sugar bacon, shiitake mushrooms, and house-made pickles. 1400 Vine St. $$$

The founders of 21c Museum Hotel set their sights on a landmark building for their second art-filled property. Technically just outside of OTR, it displays works in unexpected places; take the lobby floor, where a panel of wormlike neon patterns changes as you walk on it. Make sure to grab a drink on the rooftop terrace. 609 Walnut St. $$

Fresh off a major expansion, Washington Park (picutred)—which abuts the 1870’s-era Music Hall—hosts cultural events year-round. Don’t miss the MidPoint Music Festival (Sept. 26–28), with R&B great Shuggie Otis head-lining. 1230 Elm St.

Cincy native Sarah Jessica Parker is a fan of the chic Sloane Boutique, where owner Duru Armagan mixes pieces from established labels (Otis & Maclain; Kymerah) with homegrown brands (Brush Factory; Hark + Hark). 1216 Vine St.

Visit Japp’s and you’ll think you’ve slipped into a Prohibition-era speakeasy, where tattooed mixologist Molly Wellmann slings craft cocktails behind the bar. During happy hour (daily from 4 to 6 p.m.), gin martinis cost just 33 cents. 1134 Main St.

Family-owned Holtman’s Donuts is a cult favorite for its made-from-scratch treats. The third generation heads up the latest location, serving glazed blueberry, maple bacon, and other flavors. 1332 Vine St.

Restaurant Pricing Key
$ Less than $25
$$ $25 to $75
$$$ $75 to $150
$$$$ More than $150