The Venetian
Don't let the dizzying amount of meeting and exhibition space lead you to believe that the Venetian is simply a business hotel. It has also played host to Cigar Aficionado's Big Smoke, the Adult Video Awards, and attendees of the MAGIC fashion show. The resort's Canyon Ranch SpaClub is one of the largest and best spas in North America, and the 80-plus-store Grand Canal Shoppes is worthy of an afternoon. Every one of the 4,027 rooms is designated a suite, with a sunken living room and enormous Italian-marble bathroom.