Cheeca Lodge & Spa

In a sea of smaller boutique properties, Cheeca Lodge & Spa stands out. Located just 90 minutes from Miami International Airport, this expansive property offers a little bit of everything the Keys has to offer. In addition to its 214 well-appointed rooms and suites, decked out in a tropical-chic style, the family-friendly resort is home to 27 acres of lush gardens, a Jack Nicklaus-designed 9-hole golf course, a top-of-the-line spa, a saltwater lagoon for swimming and snorkeling, and 1,100 feet of private beachfront. Three solid eateries include a sushi lounge and the seafood-focused Atlantic's Edge (where the chef will happily prepare guests' own catch of the day).