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Cruising South America's Ruta 40

Trujillo/Paumier A road sign along Ruta 40

Photo: Trujillo/Paumier

Commonly called La Cuarenta, this famed stretch of pavement and dirt covers more than 3,000 miles from Argentina's northern border with Bolivia all the way to Cabo Virgenes in the south. It is one of the longest roads in the Americas, and along the way it crosses 18 major rivers and 236 bridges, touches 13 lakes and salt flats, and passes by 20 national parks as it follows the spine of the Andes across all manner of ecosystems and jaw-dropping topography.

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Destinations: Mendoza · Cafayate · Barreal · Villa Unión

Inspired by: Driving the Andes — by Josh Dean, Published Mar. 2006

Hotels (3)

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    Posada San Eduardo

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    Viñas de Cafayate Wine Resort

  • 201101-a-hotel-hyatt-mendoza_standard_thumb

    Park Hyatt Mendoza

    Easily the city’s finest hotel, this whitewashed, seven-floor building has a restored Spanish neoclassical exterior, a colonial-era inner courtyard... More

Restaurants (2)

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    La Palmera

Activities (2)

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    Quilmes Ruins

    In the ruin's small museum, examine arrowheads and pottery shards; outside scramble over rock walls and peer into the stone houses built into the c

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    Parque Nacional Talampaya

    Visit this under-visited national park sometimes referred to as Argentina's Grand Canyon. View the towering red cliffs and 2,000-year-old petroglyp

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Similar Trips (1)

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  • Exploring the Surreal Beauty of Salta, Argentina

    Salta, Cafayate, Cachi

    The first town, on the banks of the Calchaquíes River, is Cachi, a dusty settlement straight out of a Peckinpah western. Don’t miss the restored 18th-century adobe church in Molinos, or an espresso...


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