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Dorsoduro 173, Venice, , Italy

It’s a canal-side palazzo with a twist: Each of the 50 rooms in the 19th-century monastery turned merchant’s residence—located on one of the best spots on the Grand Canal—forsakes traditional grandeur for a design-forward sensibility, thanks to bleached-wood floors and sinuous, vibrantly hued sofas.

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Centurion Palace

It’s a canal-side palazzo with a twist: Each of the 50 rooms in the 19th-century monastery turned merchant’s residence—located on one of the best spots on the Grand Canal—forsakes traditional grandeur for a design-forward sensibility, thanks to bleached-wood floors and sinuous, vibrantly hued sofas.