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Legaspi Esquina Topete, Colonia Centro, Todos Santos, Baja California Sur 23300, Mexico

About an hour north of Cabo San Lucas in southern Baja lies the small Pacific Coast fishing town and noted artist’s colony of Todos Santos. In the heart of its colonial quarter rises a brick building that served variously as a police station, post office, and art academy for 150 years before being turned into a boutique hotel in 2010. The 14 rooms are a pleasant mix of dark wood furnishings and rustic tile floors with modern luxe amenities like plasma TVs and Egyptian-cotton sheets. In the evenings, after dinner in the courtyard restaurant, relax under the Renaissance-style ceiling of the Moorish-inflected Bar Don Guillermo—or under the stars at the rooftop lounge by the pool and spa.

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Hotel

Guaycura Boutique Hotel & Spa

About an hour north of Cabo San Lucas in southern Baja lies the small Pacific Coast fishing town and noted artist’s colony of Todos Santos. In the heart of its colonial quarter rises a brick building that served variously as a police station, post office, and art academy for 150 years before being turned into a boutique hotel in 2010. The 14 rooms are a pleasant mix of dark wood furnishings and rustic tile floors with modern luxe amenities like plasma TVs and Egyptian-cotton sheets. In the evenings, after dinner in the courtyard restaurant, relax under the Renaissance-style ceiling of the Moorish-inflected Bar Don Guillermo—or under the stars at the rooftop lounge by the pool and spa.