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Elizabeth Kiester gave up her high-powered job as the global creative director of LeSportsac to open Wanderlust on a dusty alley in Siem Reap, Cambodia, near Angkor Wat. Kiester set out to create a fashion line that is democratic in its approach (one size that really fits all), affordable (nothing over $60), and universally appealing, with a Palm Beach–meets-Phuket look. By commissioning almost everything from Cambodian artisans, she has also been helping to revive artistic traditions: a severely handicapped woman weaves $2 bracelets from plastic bottles; kids from an orphanage tie-dye $6 T-shirts; and a local seamstress creates $8 Jackie O.–style head scarves. “I love a global design dialogue,” Kiester says.