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2 Dole Dr., Los Angeles, CA 91362, United States

By pairing a luxury hotel with a state-of-the- art medical facility, this collaboration between Four Seasons and the California Health & Longevity Institute—located in a San Fernando Valley suburb only 17 miles from Malibu—introduces a new level of service (and seriousness) to the spa experience. While guest rooms are dressed in Pierre Deux fabrics, the spa takes a hard-science approach to health. A three-day package includes a physical that incorporates cancer and cholesterol screenings, a cardiac risk analysis, and a test that examines your DNA’s damage and repair mechanisms. More-traditional treatments— Swedish and shiatsu massage—are also on the menu for those simply looking to relax.

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Four Seasons Hotel Westlake Village

By pairing a luxury hotel with a state-of-the- art medical facility, this collaboration between Four Seasons and the California Health & Longevity Institute—located in a San Fernando Valley suburb only 17 miles from Malibu—introduces a new level of service (and seriousness) to the spa experience. While guest rooms are dressed in Pierre Deux fabrics, the spa takes a hard-science approach to health. A three-day package includes a physical that incorporates cancer and cholesterol screenings, a cardiac risk analysis, and a test that examines your DNA’s damage and repair mechanisms. More-traditional treatments— Swedish and shiatsu massage—are also on the menu for those simply looking to relax.