The Jefferson, Washington, D.C.

This 99-room Beaux-Arts landmark reopened in 2009 after a two-year, floor-to-ceiling overhaul. Thomas Jefferson-inspired design details abound, ranging from toile drapes to three-inch-thick doorframes in guest rooms, just like those at Monticello. In the hotel’s clubby bar, Quill, a series of 18th-century maps trace the former president’s wine tours through France, Germany, and Italy. The finest display, however, might be the hand-painted silk mural in the hotel restaurant, Plume, depicting the south vineyard at Monticello. Plume has quickly become a D.C. favorite for its inventive European fare. (A glass barrel-vaulted ceiling also makes it one of the city’s most stunning restaurants.)