Nylo

At the chain's first outpost, in Plano, Texas, pod chairs and glass "antler" chandeliers hang from the ceiling, and a "game room/library" is outfitted with pink cowhide rugs, Ultrasuede banquettes, and a stainless-steel bar. For the more uptight traveler, Nylo also offers an entire floor of 47 anti-allergen rooms. They are kept contaminant-free with air-purifiers, hypoallergenic linens, and a patented "Pure shield," applied to surfaces in rooms to keep the dust off.