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Hotels in Central South Carolina

From luxury resorts to small design hotels and cozy inns, there are an infinite number of great places to stay in the world, including hotels in Central South Carolina. Browse our travel guide and get Travel + Leisure’s picks for the best Central South Carolina hotels—all-inclusive resorts, design hotels, remote lodges, vacation rentals, and more. Our international team of editors and writers handpicks the top Central South Carolina hotels, helping travelers discover the most popular places to stay in Central South Carolina, and the most memorable.

Whether a boutique hotel with luxury amenities, a wilderness lodge, a cool rental home, or a country inn fit for your budget, Travel + Leisure highlights the best of the best. From affordable beach resorts and cozy inns to high-tech hotels and kid-friendly all-inclusive resorts, these Central South Carolina hotel listings will help you find just the right place to spend the night during your visit. Below find Travel + Leisure’s top spots for where to stay in Central South Carolina.

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  • Ambrias Garden Manor

    PRICE RANGE: Dollar
    Located minutes from the interstate, this 1920s Victorian mansion has romantic appeal thanks to flowered grounds, featuring multi-colored camellias... More
  • Sandhurst Estate Bed & Breakfast Inn

    PRICE RANGE: Dollar
  • 201207-v-hotels-the-willcox_standard_thumb

    The Willcox

    PRICE RANGE: Dollar
    Flanked by grand white pillars and big oak trees, The Willcox is filled with historic southern charm. You’ll feel like you’ve stepped into Scarlett... More

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