Refined low-country cottage resort, framed by Spanish moss, on tidal stretch of May River.
Stats: 50 cottages; 4 restaurants; 2 bars.
Rooms to book: Cottages Suites have antique pine floors, fireplaces, plasma TVs, and screened verandas.
Insider tip: Bikes, kayaks, canoes—and s’mores kits, after 8pm—are free to guests.
Cost: Doubles from $650.
See the full list of the T+L 500 | 2010.