Domaine des Andéols—a rural hotel coaxed out of a hamlet of farmhouses in the Lubéron—is reinventing the south of France experience. Interiors of the nine stone buildings reject the region's familiar rush-seated furniture and sunflower still lifes in favor of Mies van der Rohe leather lounges and Andy Warhol serigraphs. Houses have one to three bedrooms, and include proper salons, dining rooms, and kitchenettes. Guests can alternate between tossing their own salads and dining at the Knoll-furnished restaurant. Not content with being the most progressive hotel in France, Andéols also has artistic ambitions: currently under way is an exhibition of photographs by Ellen von Unwerth, known for shooting vamps and vixens. Domaine des Andéols, Les Andéols, St.-Saturnin-Les-Apt; 33-4/90-75-50-63; www.domainedesandeols.com; houses from $657.
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