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Why Go Now Chile's capital has never been more spirited—or stylish. A downtown revival anchored by the Centro Cultural Palacio de la Moneda, neighborhoods like Barrio Bellas Artes, and projects tied to the country's bicentennial in 2010 are changing the city's look. And now there's the Museo de la Moda, Latin America's first fashion museum. The state-of-the-art facility, bankrolled by textile scion Jorge Yarur Bascuñán, features an 8,000-piece collection spanning four centuries. Its first show, "Dressing the Time," running through December, is a survey ranging from 18th-century French finery to 1970's English punk. 4562 Avda. Vitacura, 56-2/219-3623; museodelamoda.cl.—Connie McCabe
Stay After a $10 million renovation, the Grand Hyatt Santiago (4601 Avda. Kennedy; 56-2/950-1234; doubles from $388; santiago.grand.hyatt.coml) has a Japanese restaurant, a three-story Ako spa, and 310 refurbished rooms—those on floors 16 through 18 have breathtaking views of the Andes.
Eat Crispy Chilean-sausage egg rolls and tender Wagyu beef draw meat lovers to Ox (3960 Nueva Costanera; 56-2/799-0260; dinner for two $42), the city's newest—and best—parilla fina, or fine-dining steak house.
Don't Miss The Avenida Alonso de Córdova has the best shopping. Besides Armani and Hermès, you'll find Chilean boutiques like Zapatera (3834 Avda. Alonso de Córdova; 56-2/206-6585; zapatera.cl), where designer Javiera Munizaga's shoes (zebra-patterned flats, alligator stilettos) are favorites of the well-heeled.
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