These days, it's hard to look fabulous at 36,000 feet. Enter Stefano Pilati, the designer who's been perfecting feminine refinement at Yves Saint Laurent since 2004. His newest collection, Edition 24 (212/980-2970; at YSL boutiques), is a 50-piece line designed to cross multiple time zones. Everything, from trenches to skirts to turtlenecks, is wrinkle-resistant and can be combined and layered to create 24 uncomplicated looks. Our favorite part: the matching luggage set—roller suitcase ($3,595), laptop case, and oversize Downtown cabin bag, available in leopard-print calf, gray flannel, and black patent leather. Roll this, and you're sure to be runway-ready.