The latest addition to the grand Paseo de la Reforma is the St. Regis Mexico City (doubles from $430). Inside, 189 neutral-toned, Yabu Pushelberg–designed rooms have floor-to-ceiling windows with panoramic views of the city center. Amid the luxury-brand shops of the upscale Polanco district, north of the city’s Chapultepec Park, Las Alcobas (doubles from $275), also by Yabu Pushelberg, is refreshingly intimate: beds in the 35 rooms are covered with embroidered linens, while bathrooms have whirlpools and steam jets. You’ll find a younger vibe at Great Value Room Mate Valentina (doubles from $150), which opened in April in midtown’s Zona Rosa nightlife hub. Magenta sofas and textured wall patterns add a playful touch to the 62 sleek, white rooms. And southeast of the park, in chic and leafy Condesa, Great Value Condesa DF (doubles from $175; dinner for two $80) has become one of the city’s most fashionable addresses, thanks to its buzzy scene (including the popular El Patio Japanese-Mexican fusion restaurant) and relaxed, vintage-inspired design.